This will depend on the amount of time you have available and your budget. There is enough to see on the North Coast to keep you busy for two weeks. From West to East: Monte Cristi (Playa El Morro and Cayos 7 Hermanos); Punta Rucia (Cayo Arenas), Luperón and La Isabela (where Columbus built the first settlement in the Americas), Puerto Plata city (Amber Museum, Brugal rum factory, Columbus Water Park), Playa Dorada (for night time discotheque dancing and shopping at the mall), Sosua Beach, Cabarete Beach, Rio San Juan and Pueblito Principe, Playa Grande (excellent beach and excellent golf), and then East to Samaná with Las Galeras, Las Terrenas, Cayo Levantado....