I just checked Bureo (a sort of local guide to dining) and there doesn't seem to be a whole lot to choose from inthe Zona Colonial.
I found:
Anacaona LaTaberna at Isabel la Católica and the corner of El Conde.
Le Patio on Mercedes corner of Meriño
La Atarazana on La Atarazana #5
Of course you can never go wrong at Vesuvios on the malecón or at la Reina de España on Cervantes 105
Good Eating.
HB

