If you are headed for Sosua, then take a taxi to Caribe Tours and take the bus to Sosua. I prefer Metro, but Caribe Tours has more buses. Metro has buses that go to Sosua leaving SD at 8:20, 10:20, 3:20 and 5:50. Caribe Tours, however, has a bus leaving every hour on the hour from about 6 am to 7 pm. Caribe Tour has good buses and its ticket is a bit cheaper than Metro. But the advantage is the frequency of departures for Sosua compared to Metro.
But it is true that Caribe Tours terminal is in Charamicos while Metro is in El Batey (the farmacia on the property the Texaco station is on.
Going back to SD, I'd suggest Metro if its schedule works for you. Departures for SD are at 8:20, 10:20 am, 1:20 and 5:50 pm. Otherwise take Caribe Tours with hourly departures at 20 minutes past the hour.
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