Mountain frog is right. Once you go to the Samana Peninsula, the rest of the DR will never look or feel the same. On our first trip to the DR my husband and I lucked out and got booked into a resort on the Peninsula. It made a HUGE impression on us We've only been back once since then, but it is still one of our favourite places.
I am not sure if I would recommend newcomers to drive it though. I am not by far the most experienced traveller in the DR, but I wouldn't even think of renting a car. I know my limits and leave the driving to the professionals, especially for a relatively long distance as that. I like to see the scenrey and country side, not my white kniucles on the steering wheel

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Rose