I think that if you can tell the driver precisely where the
parada de guaguas is (not guaguas parada!!) he will quote you a price. This you can compare to the prices listed there at the airport for travel into town. Too high, you diddle a bit, or just walk away. Ask another one.
I would say that it is safe and also recommend that you exchange some money there at the airport so you are not flashing US currency around.
Should be no problem.
If you are friendly with your fellow passengers on the plane you might get a offer for a lift into town. This happens a lot.
HB

